Lundbeck Seattle BioPharmaceuticals

Senior Development Associate I

Requisition ID: 1756

Do you want to join a team where the mission is meaningful, the challenges are complex, and you can directly see the results of your hard work? Lundbeck Seattle BioPharmaceuticals (Lu-SBP), located in Bothell, Washington, is the Process Development Center of Excellence for Biologics within the global Lundbeck CMC organization. Since integrating into Lundbeck in October 2019, Lu-SBP has supported commercial launch of Lundbeck’s first biologic product (Vyepti) and advancement of a growing biologics pipeline in collaboration with our Copenhagen-based Late-Stage Development and Production groups. The Lu-SBP team leads and supports the development of new product candidates from cell line development through commercial validation of Drug Substance and Drug Product manufacturing processes. Join us on our journey of progress & innovation dedicated to addressing the vast unmet medical needs associated with brain disease!

SUMMARY

The Downstream Process Development group is seeking an individual to be part of a team developing expression and purification processes for antibody candidates supporting preclinical and clinical development. The primary responsibility is to rapidly identify scalable purification methods for new antibodies and support these processes to clinical scale.

ESSENTIAL FUNCTIONS

• Screen lead antibody and cell line candidates for appropriate development characteristics
• Purify and formulate antibody preparations to support analytical and pre-clinical studies
• Collaborate in purification development from multiple expression platforms
• Perform purification process transfer internally and externally
• Design and execute purification screening, scouting and characterization experiments
vWork collaboratively with upstream process development and analytical development groups
• Creates written reports on experimental design, analysis and conclusions, and deliver presentations on findings

REQUIRED EDUCATION, EXPERIENCE and SKILLS

• Accredited Bachelor’s degree and 5+ years’ experience in biopharmaceutical industry or relevant combination of education and experience totaling 9+ years
• Extensive experience purifying proteins using column chromatography
• Skilled in Unicorn-based AKTA programming and result evaluation.

PREFERRED EDUCATION, EXPERIENCE and SKILLS

• Accredited Bachelor’s degree or Master’s degree in biochemistry, chemistry or related discipline
• Strong resin chemistry knowledge
• Familiarity with antibody purification scale-up and manufacturing considerations
• Wide background in protein analytical techniques
• Labkey familiarity
• Experienced with plate-based screening methods
• Octet and Surface Plasmon Resonance experience
• Working knowledge of JMP statistical analysis software

Lundbeck is unique from other biopharmaceutical companies in that we are 70 percent owned by a research-focused foundation. We have a deep heritage of discovery and have brought breakthrough therapies to millions of people across the globe. And we're just getting started! Our success is driven by our great people and inclusive culture, which is guided by our beliefs of being Patient-Driven, Courageous, Ambitious, Passionate & Responsible. Are you ready to make an impact, one patient at a time?

Lundbeck offers a robust and comprehensive benefits package to help employees live well and protect their health, family, and everyday life. Information regarding our benefit offering can be found on the U.S. career site.

Lundbeck is committed to working with and providing reasonable accommodations to disabled veterans and other individuals with disabilities during our employment application process. If, because of a disability, you need a reasonable accommodation for any part of the application process, please visit the U.S. career site.

Lundbeck is proud to be an equal opportunity workplace and is an affirmative action employer. We are committed to equal employment opportunity regardless of race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status, and any other characteristic protected by law, rule, or regulation. Lundbeck participates in E-Verify.

APPLY:

Lundbeck Seattle BioPharmaceuticals
Reference Job Code: 1756

Lundbeck Seattle BioPharmaceuticals is an Equal Opportunity Employer

Submitted: 03/24/2021